Biosintesis de esteroides en el ovario

In order to investigate the in vitro steroidogenic capacity of glands at different ages, minces of testicular tissue were incubated with labelled precursors. The studies were conducted in triplicate at 35°C. For equal quantities of incubated tissue the non-metabolized amount of [ 3 H]pregnenolone and [ 14 C]progesterone, utilized as precursors, was different in post-pubertal and senescent animals: ± 3 vs ± % ( P < ) for pregnenolone, and ± vs ± % ( P < ) for progesterone, respectively. Testosterone production was 12 ± 2% in adult and ± % in senescent animals ( P < ). The testosterone/ androstenedione ratio was not significently different in post-pubertal and senescent animals: ± vs ± , but consistently higher than found in immature animals: ± . The lesser potential capacity of the aging tissue to synthesize testosterone could be explained by a decline in the glands capacity to metabolize the hormonal precursors.

Biosintesis de esteroides en el ovario

biosintesis de esteroides en el ovario

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biosintesis de esteroides en el ovariobiosintesis de esteroides en el ovariobiosintesis de esteroides en el ovariobiosintesis de esteroides en el ovariobiosintesis de esteroides en el ovario

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