Schalt-Impuls für beide Richtungen ausgelöst mit dem Schleifer Switching impulse activated in both directions by pickup shoe Impulsion de commande par frotteur pour deux sens de circulation Rijrichtingsafhankelijke schakelimpuls . het sleepcontact Impulso eléctrico válido para los dos sentidos de marcha efectuado con el patín Impulso di commutazione per entrambe le direzioni inviato tramite il pattino Kopplingsimpulsen för båda riktningarna utlösta via släpskon Kontakt-impuls udiøst for begge retninger med slæberen...
Issue (and what should be considered)
Quality of evidence
Strong recommendations usually require at least
moderate-quality evidence for all the critical outcomes. The lower the
quality of evidence, the less likely there should be a strong
Relative importance of the outcomes
(benefits, harms, burdens) Authors and editors consider the relative values and preferences that patients and other stakeholders place on outcomes and the variability in values and preferences across patients. If values and preferences vary widely, a strong recommendation becomes less likely. Baseline risks of adverse outcomes
(typically most relevant for benefits) The higher the baseline risk of an adverse outcome, the greater the magnitude of benefit a treatment will offer, and the more likely there should be a strong recommendation. If the baseline risk is very different for two subpopulations, then UpToDate may make separate recommendations for these different groups. Magnitude of effect (benefits - eg,
reduction in RR; harms - eg, increase in RR; burden) Larger relative risk reductions with treatment make a strong recommendation for treatment more likely, while larger increases in the relative risk of harms make a strong recommendation for treatment less likely. Absolute magnitude of the effect (benefits,
harms, burden) The larger the absolute benefits with treatment, the greater the likelihood of a strong recommendation in favor of treatment. The larger the absolute increase in harms, the less likely there should be a strong recommendation in favor of treatment. Precision of the estimates of the effects
(benefits, harms and burdens) The greater the precision, the more likely there should be a strong recommendation. Cost The higher the incremental cost, the less the likelihood of a strong recommendation in favor of a treatment.
"Earlier, in quiet times, the village of Two Bergen was not so lively. It got its name because of the beautiful location where it was founded 540 years ago. There was the valley, nicely cut out between the two peaks. There was only a limited service, with a small slow train two times per day. Then, there was Frederikshaven, the harbor, where most of the people living in Two Bergen were employed. Many of them worked in the shipyard. The goods for both the village and the shipyard arrived in the harbor, where the goods for the village were further transported by train.