Gliukokortikoidai kortikosteroidai

Glucocorticoids influence all types of inflammatory events, no matter what their cause. They induce the lipocortin-1 (annexin-1) synthesis, which then binds to cell membranes preventing the phospholipase A2 from coming into contact with its substrate arachidonic acid . This leads to diminished eicosanoid production. The cyclooxygenase (both COX-1 and COX-2) expression is also suppressed, potentiating the effect. In other words, the two main products in inflammation Prostaglandins and Leukotrienes are inhibited by the action of Glucocorticoids.

A short review is given of the mechanisms associated with the development of osteoporosis in the excess of glucocorticoids and the medication for preventing and treating bone loss. Reviews User-contributed reviews Add a review and share your thoughts with other readers. Be the first. Add a review and share your thoughts with other readers. Be the first.
Tags Add tags  for "Z glukokortikoidi povzročena osteoporoza = Osteoporosis caused by glucocorticoids". Be the first. Similar Items Related Subjects: (4)

  • Osteoporosis.
  • Glucocorticoids.
  • Osteoporoza.
  • Glukokortikoidi.
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Gliukokortikoidai kortikosteroidai

gliukokortikoidai kortikosteroidai

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gliukokortikoidai kortikosteroidai

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