Initial dose: 75 mg subcutaneous injection every 2 weeks
Maximum dose: 150 mg subcutaneous injection every 2 weeks, if the LDL-C response to initial dose is inadequate
Comments: Measure LDL-C levels within 4 to 8 weeks of initiation or titration to assess response; adjust the dose, if needed.
Uses: Adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease, who require additional lowering of LDL-C
A separate but often conflated issue is whether to use configuration files or code on an API to wire up services. For most applications that are likely to be deployed in many places, a separate configuration file usually makes most sense. Almost all the time this will be an XML file, and this makes sense. However there are cases where it's easier to use program code to do the assembly. One case is where you have a simple application that's not got a lot of deployment variation. In this case a bit of code can be clearer than a separate XML file.