The initial dosage of prednisolone sodium phosphate oral solution may vary from 5 mL to 60 mL (5 to 60 mg prednisolone base) per day depending on the disease being treated. Prednisolone sodium may interact with barbiturates, phenytoin, ephedrine, rifampin, cyclosporine, estrogens , ketoconazole, warfarin, aspirin or other non-steroidal anti-inflammatory drugs ( NSAIDs ), diuretics , amphotericin-B, digitalis, anticholinesterase drugs, certain vaccines , and anti-diabetic medications. Tell your doctor all medications and supplements you use and all vaccines you recently received. During pregnancy, prednisolone sodium should be used only if prescribed. Prednisolone sodium passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.
Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes.